Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.44 |
| ▸ | CA2 | P00918 | 9/20 | 0.44 |
| ▸ | CA12 | O43570 | 8/20 | 0.44 |
| ▸ | CA9 | Q16790 | 8/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026297 | 0.91 | PTGS2 (0.53) | PTGS2PTGS1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL8551969 | 0.83 | PTGS2 (0.49) | CA1CA2CA12CA9CA14 | |
| SCHEMBL8549359 | 0.80 | PTGS2 (0.52) | CA1CA2CA12CA9CA14 | |
| SCHEMBL6002469 | 0.80 | PTGS2 (0.50) | CA1CA2CA12CA9CA14 | |
| SCHEMBL5823861 | 0.80 | PTGS2 (0.50) | CA1CA2CA12CA9CA14 | |
| SCHEMBL9026427 | 0.80 | PTGS2 (0.43) | PTGS2PTGS1HPGDCYP2C19NR4A2 | |
| SCHEMBL8550926 | 0.80 | PTGS2 (0.52) | CA1CA2CA12CA9CA14 | |
| SCHEMBL9097737 | 0.80 | PTGS2 (0.46) | CA1CA2CA12CA9CA14 | |
| SCHEMBL9025935 | 0.79 | PTGS2 (0.55) | PTGS2PTGS1LMNAALDH1A1CYP2C19 | |
| SCHEMBL9026123 | 0.79 | PTGS2 (0.55) | PTGS2PTGS1LMNAALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699192-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-06 | — | — | EP | claimed |
| WO-1994027980-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1994-12-08 | — | — | WO | claimed |