Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039524 | 0.86 | ADORA3 (0.50) | ADORA2BADORA3MEN1KMT2A | |
| SCHEMBL9040140 | 0.82 | ADORA2A (0.51) | ADORA2B | |
| SCHEMBL9038987 | 0.80 | MEN1 (0.48) | ADORA2BADORA3HPGDMEN1KMT2A | |
| SCHEMBL9038623 | 0.79 | PDE1A (0.54) | ADORA2BCYP3A4SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9536256 | 0.77 | TAS2R14 (0.45) | ADORA2BADORA3KMT2AALDH1A1LMNA | |
| SCHEMBL9039108 | 0.76 | PNP (0.58) | ADORA3HPGDMEN1KMT2ACYP3A4 | |
| SCHEMBL9039440 | 0.74 | ADORA2A (0.51) | ADORA2BPKM | |
| SCHEMBL9119046 | 0.74 | ADORA2B (0.81) | ADORA2BADORA3KMT2ACYP3A4POLB | |
| SCHEMBL13941407 | 0.73 | HPGD (0.58) | ADORA2BADORA3HPGDMEN1KMT2A | |
| SCHEMBL23974590 | 0.72 | ADORA2A (0.63) | ADORA2BADORA3HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696590-A1 | Pyrido[2,3-d]pyrimidine derivatives, their preparation and their use as anti-asthma agents | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |