Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 13/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CCKAR | P32238 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040117 | 0.89 | CCKBR (0.51) | CCKBRCCKARL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9039509 | 0.87 | CCKBR (0.55) | CCKBRCCKARALDH1A1 | |
| SCHEMBL9040261 | 0.87 | CCKBR (0.50) | CCKBRCCKARALDH1A1 | |
| SCHEMBL9039519 | 0.87 | CCKBR (0.60) | CCKBRCCKAR | |
| SCHEMBL9039128 | 0.86 | CCKBR (0.73) | CCKBR | |
| SCHEMBL9040629 | 0.85 | CCKBR (0.57) | CCKBRCCKAR | |
| SCHEMBL9048213 | 0.84 | CCKBR (0.51) | CCKBRMAPK1TSHRALDH1A1 | |
| SCHEMBL9039747 | 0.84 | CCKBR (0.51) | CCKBRMAPK1TSHR | |
| SCHEMBL9040702 | 0.84 | CCKBR (0.51) | CCKBRMAPK1KMT2AMAPTTSHR | |
| SCHEMBL9043246 | 0.84 | CCKBR (0.57) | CCKBRMAPK1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703222-A1 | 3-AMINOAZEPINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-03-27 | — | — | EP | disclosed |