Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.45 |
| ▸ | PDE4A | P27815 | 4/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCND2 | P30279 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040427 | 0.82 | ADORA2A (0.41) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL9038556 | 0.81 | PDE4B (0.44) | PDE4BADORA2APDE4APDE4CPDE4D | |
| SCHEMBL9038149 | 0.78 | ADORA2A (0.49) | PDE4BADORA2APDE4APDE4CPDE4D | |
| SCHEMBL9037741 | 0.77 | ADORA2B (0.40) | PDE4BADORA2APDE4APDE4CPDE4D | |
| SCHEMBL9038040 | 0.75 | PDE4B (0.43) | PDE4BADORA2APDE4APDE4CPDE4D | |
| SCHEMBL9039306 | 0.73 | PDE4B (0.43) | PDE4BADORA2APDE4APDE4CPDE4D | |
| SCHEMBL9039080 | 0.72 | ADORA2A (0.46) | ADORA2AADORA3ADORA2BMEN1KMT2A | |
| SCHEMBL9037748 | 0.72 | AURKA (0.39) | UTS2R | |
| SCHEMBL9037826 | 0.69 | KMT2A (0.50) | ADORA3MEN1KMT2A | |
| SCHEMBL1713392 | 0.69 | FEN1 (0.60) | PDE4BADORA2APDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696590-A1 | Pyrido[2,3-d]pyrimidine derivatives, their preparation and their use as anti-asthma agents | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |