Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11446784 | 0.87 | P2RX7 (0.44) | P2RX7MEN1KMT2AEPHX2GRIN2D | |
| Hydrochloric Acid SCHEMBL11447298 | 0.86 | MEN1 (0.45) | P2RX7MEN1KMT2AEPHX2GRIN2D | |
| SCHEMBL3249734 | 0.74 | CYP2D6 (0.47) | P2RX7MEN1KMT2AEPHX2ALDH1A1 | |
| SCHEMBL3175880 | 0.73 | P2RX7 (0.48) | P2RX7MEN1KMT2AEPHX2 | |
| SCHEMBL14510877 | 0.73 | MEN1 (0.62) | P2RX7MEN1KMT2AEPHX2ALDH1A1 | |
| SCHEMBL4846108 | 0.72 | ALDH1A1 (0.47) | P2RX7MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL25567710 | 0.71 | P2RX7 (0.43) | P2RX7MEN1KMT2AEPHX2ALDH1A1 | |
| SCHEMBL4936872 | 0.70 | ALDH1A1 (0.47) | P2RX7MEN1KMT2AEPHX2ALDH1A1 | |
| SCHEMBL27463437 | 0.69 | KMT2A (0.55) | P2RX7MEN1KMT2AEPHX2 | |
| SCHEMBL30985760 | 0.68 | SIGMAR1 (0.34) | P2RX7MEN1KMT2AEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695297-A1 | 1,5-BENZODIAZEPINES USEFUL AS GASTRIN OR CCK-ANTAGONISTS | GLAXO S.p.A. (IT) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994025445-A1 | 1,5-BENZODIAZEPINES USEFUL AS GASTRIN OR CCK-ANTAGONISTS | GLAXO S.P.A. (IT) | 1994-11-10 | — | — | WO | disclosed |