SCHEMBL4846108

SCHEMBL4846108

Nc1cccc(C23CC4CC(CC(C4)C2)C3)c1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
LMNA P02545 4/20 0.47
P2RX7 Q99572 2/20 0.39
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
GRIN3A Q8TCU5 1/20 0.37
MAPT P10636 1/20 0.37
CD44 P16070 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
GFER P55789 1/20 0.35
RARB P10826 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25125099 0.86 ALDH1A1 (0.48) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL21409852 0.82 CD44 (0.34) ALDH1A1LMNAP2RX7MAPTCD44
SCHEMBL28090099 0.75 GRIN1 (0.39) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL548737 0.75 MEN1 (0.46) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL9721521 0.73 HSD11B1 (0.42) ALDH1A1LMNAP2RX7GRIN2DGRIN3B
SCHEMBL31434421 0.73 GRIN2D (0.39) ALDH1A1LMNAP2RX7GRIN2DGRIN3B
SCHEMBL9038705 0.72 P2RX7 (0.43) ALDH1A1LMNAP2RX7GRIN2DGRIN3B
SCHEMBL21873616 0.71 LMNA (0.37) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL3043614 0.71 SLC6A3 (0.41) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL3759976 0.71 MEN1 (0.46) ALDH1A1LMNAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785841-B2 Compound, display panel and display apparatus WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-10-10 US disclosed
US-11674920-B2 Moisture-sensitive film and sensor using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-06-13 US disclosed
US-20210055247-A1 MOISTURE-SENSITIVE FILM AND SENSOR USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-02-25 US disclosed
US-20200373493-A1 COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-11-26 US disclosed
US-7365231-B2 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2008-04-29 US disclosed
US-7365231-B2 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2008-04-29 US disclosed
US-20060241187-A1 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2006-10-26 US disclosed
US-20060241187-A1 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2006-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200373493-A1 COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS C1S, CDK20, CEP170 ALDH1A1 1239/4885LMNA 2044/4885P2RX7 766/4885
US-20060241187-A1 Compound with antitumor activity and preparation method therefor WEE1, WEE2, CYP51A1 ALDH1A1 206/4885LMNA 2945/4885P2RX7 774/4885
US-11785841-B2 Compound, display panel and display apparatus C1S, CDK20, CEP170 ALDH1A1 1239/4885LMNA 2044/4885P2RX7 766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.