Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 2/20 | 0.40 |
| ▸ | PYGM | P11217 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799468 | 0.81 | SCN9A (0.56) | SCN9APYGLPYGM | |
| SCHEMBL7423602 | 0.81 | SCN9A (0.56) | SCN9APYGLPYGM | |
| SCHEMBL4799483 | 0.81 | SCN9A (0.56) | SCN9APYGLPYGM | |
| SCHEMBL9040545 | 0.81 | CCKBR (0.45) | CCKBR | |
| SCHEMBL24991617 | 0.76 | RIPK1 (0.53) | SCN9AKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL19880693 | 0.76 | RIPK1 (0.53) | SCN9AKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL19207938 | 0.76 | RIPK1 (0.53) | SCN9AKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL19224577 | 0.76 | RIPK1 (0.53) | SCN9AKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL19255505 | 0.76 | RIPK1 (0.53) | SCN9AKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL19228387 | 0.76 | RIPK1 (0.53) | SCN9AKDM1AMAOBKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703222-A1 | 3-AMINOAZEPINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-03-27 | — | — | EP | disclosed |