Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040544 | 0.96 | L3MBTL1 (0.49) | PTGDR2L3MBTL1SMN1; SMN2NPSR1AGTR1 | |
| SCHEMBL9041639 | 0.92 | SMN1; SMN2 (0.52) | L3MBTL1SMN1; SMN2NPSR1ALDH1A1LMNA | |
| SCHEMBL9044249 | 0.89 | PTGDR2 (0.59) | PTGDR2L3MBTL1SMN1; SMN2NPSR1AGTR1 | |
| SCHEMBL9040518 | 0.88 | MMP7 (0.53) | L3MBTL1SMN1; SMN2NPSR1AGTR1AGTR2 | |
| SCHEMBL8393455 | 0.88 | AGTR1 (0.54) | PTGDR2L3MBTL1AGTR1AGTR2PPARG | |
| SCHEMBL9041236 | 0.86 | AGTR1 (0.66) | AGTR1AGTR2PPARG | |
| SCHEMBL9043483 | 0.85 | PPARG (0.67) | AGTR1AGTR2PPARG | |
| SCHEMBL9040948 | 0.84 | L3MBTL1 (0.55) | PTGDR2L3MBTL1SMN1; SMN2NPSR1AGTR1 | |
| SCHEMBL9042213 | 0.84 | PPARG (0.47) | L3MBTL1SMN1; SMN2AGTR1AGTR2ALDH1A1 | |
| SCHEMBL9043476 | 0.84 | PPARG (0.65) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |