Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040948 | 0.95 | L3MBTL1 (0.55) | PTGDR2L3MBTL1AGTR1AGTR2PPARG | |
| SCHEMBL9040448 | 0.91 | SMN1; SMN2 (0.56) | L3MBTL1AGTR1AGTR2PPARGSMN1; SMN2 | |
| SCHEMBL9039348 | 0.89 | PTGDR2 (0.52) | PTGDR2L3MBTL1AGTR1AGTR2PPARG | |
| SCHEMBL9040258 | 0.87 | SMN1; SMN2 (0.51) | L3MBTL1AGTR1AGTR2PPARGSMN1; SMN2 | |
| SCHEMBL8393270 | 0.87 | AGTR1 (0.71) | PTGDR2L3MBTL1AGTR1AGTR2PPARG | |
| SCHEMBL9041377 | 0.85 | AGTR1 (0.74) | AGTR1AGTR2PPARG | |
| SCHEMBL9040544 | 0.84 | L3MBTL1 (0.49) | PTGDR2L3MBTL1AGTR1AGTR2PPARG | |
| SCHEMBL9041515 | 0.84 | PPARG (0.74) | AGTR1AGTR2PPARG | |
| SCHEMBL9041506 | 0.82 | PPARG (0.73) | AGTR1AGTR2PPARG | |
| SCHEMBL9042087 | 0.82 | PPARG (0.56) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |