SCHEMBL903984 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	GPR119	Q8TDV5	12/20	0.50

▸	CYP4F2	P78329	3/20	0.43

▸	CYP4A11	Q02928	3/20	0.43

▸	KDM4E	B2RXH2	1/20	0.41

▸	NPC1	O15118	1/20	0.41

▸	RAB9A	P51151	1/20	0.41

▸	PRMT5	O14744	1/20	0.38

▸	KDR	P35968	1/20	0.36

▸	ETV6	P41212	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1093041	0.87	GPR119 (0.56)	GPR119CYP4F2CYP4A11KDM4ENPC1
SCHEMBL10067601	0.80	GPR119 (0.42)	GPR119CYP4F2CYP4A11KDM4ENPC1
SCHEMBL904059	0.80	GPR119 (0.42)	GPR119CYP4F2CYP4A11KDM4ENPC1
SCHEMBL904048	0.78	GPR119 (0.46)	GPR119KDM4ENPC1RAB9A
SCHEMBL1091938	0.76	GPR119 (0.50)	GPR119CYP4F2CYP4A11KDM4ENPC1
SCHEMBL903971	0.75	CHRNA3 (0.47)	GPR119
SCHEMBL10067420	0.74	GPR119 (0.47)	GPR119
SCHEMBL1092523	0.74	GPR119 (0.53)	GPR119CYP4F2CYP4A11KDM4ENPC1
SCHEMBL904119	0.74	GPR119 (0.47)	GPR119
SCHEMBL904090	0.73	GPR119 (0.41)	GPR119KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012041158-A1	TRICYCLIC COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF	上海恒瑞医药有限公司 (CN)	2012-04-05	—	—	WO	disclosed