Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ME2 | P23368 | 3/20 | 0.43 |
| ▸ | ME1 | P48163 | 3/20 | 0.43 |
| ▸ | ME3 | Q16798 | 3/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038616 | 0.88 | MAPT (0.54) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL20639883 | 0.87 | PPARD (0.41) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL9118588 | 0.85 | METAP2 (0.42) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL9384752 | 0.84 | MAPT (0.58) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL9665897 | 0.83 | MAPT (0.65) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL7458461 | 0.81 | MAPT (0.56) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL9665027 | 0.81 | MAPT (0.62) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL14764336 | 0.80 | MAPT (0.65) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL8506763 | 0.79 | MAPT (0.55) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL7834009 | 0.79 | MAPT (0.64) | MAPTKDM4ELMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402989-B1 | Antifungal 4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]triazolones and imidazolones | JANSSEN PHARMACEUTICA NV (BE) | 1996-04-03 | — | — | EP | disclosed |
| US-5075309-A | For prevention and treatment of fungal diseases in mammals | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-12-24 | — | — | US | disclosed |
| EP-0402989-A2 | Antifungal 4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]triazolones and imidazolones | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-12-19 | — | — | EP | disclosed |