Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348825 | 0.80 | GAA (0.34) | ALDH1A1KDM4E | |
| SCHEMBL9040147 | 0.71 | ALDH1A1 (0.34) | ALDH1A1SOAT1 | |
| SCHEMBL9344735 | 0.64 | GAA (0.33) | ALDH1A1KDM4E | |
| SCHEMBL6210740 | 0.63 | CHRNB2 (0.35) | ALDH1A1SOAT1 | |
| SCHEMBL2409560 | 0.63 | CHRM1 (0.42) | ALDH1A1 | |
| SCHEMBL9568980 | 0.60 | ALDH1A1 (0.38) | ALDH1A1KDM4ESOAT1 | |
| SCHEMBL30998306 | 0.60 | PPM1B (0.44) | ALDH1A1 | |
| SCHEMBL17231979 | 0.59 | — | — | |
| SCHEMBL10963921 | 0.59 | — | — | |
| SCHEMBL12507466 | 0.59 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481274-B1 | 7-(2,7-Diazabicyclo[3.3.0]octyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1996-10-23 | — | — | EP | disclosed |
| EP-0393424-B1 | Process for the preparation of 2,7-Diazabicyclo(3.3.O)octanes | BAYER AG (DE) | 1995-09-27 | — | — | EP | disclosed |
| EP-0481274-A1 | 7-(2,7-Diazabicyclo[3.3.0]octyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1992-04-22 | — | — | EP | disclosed |
| EP-0393424-A2 | Process for the preparation of 2,7-Diazabicyclo(3.3.O)octanes | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |