Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | PDE6D | O43924 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9041947 | 0.90 | PPARG (0.51) | PPARGAGTR1AGTR2PDE6DDRD2 | |
| SCHEMBL9040689 | 0.88 | TNF (0.59) | PPARGAGTR1AGTR2PDE6DDRD2 | |
| SCHEMBL9040956 | 0.88 | ALDH1A1 (0.61) | PPARGPDE6DDRD2TBXA2RALDH1A1 | |
| SCHEMBL9039784 | 0.86 | PPARG (0.46) | PPARGAGTR1AGTR2DRD2TBXA2R | |
| SCHEMBL9042383 | 0.86 | PPARG (0.60) | PPARGAGTR1AGTR2LMNAHTT | |
| SCHEMBL9040258 | 0.85 | SMN1; SMN2 (0.51) | PPARGAGTR1AGTR2ALDH1A1LMNA | |
| SCHEMBL9041999 | 0.85 | PDE6D (0.56) | PPARGPDE6DDRD2TBXA2RALDH1A1 | |
| SCHEMBL9041160 | 0.85 | HDAC1 (0.58) | PPARGAGTR1AGTR2SMN1; SMN2 | |
| SCHEMBL9041506 | 0.84 | PPARG (0.73) | PPARGAGTR1AGTR2 | |
| SCHEMBL9038767 | 0.84 | MEN1 (0.59) | PPARGAGTR1AGTR2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |