Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | GALR3 | O60755 | 2/20 | 0.55 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.50 |
| ▸ | PTAFR | P25105 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | PDE6D | O43924 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040956 | 0.89 | ALDH1A1 (0.61) | PPARGPDE6DHRH3DRD2TBXA2R | |
| SCHEMBL9041947 | 0.89 | PPARG (0.51) | PPARGAGTR1AGTR2PDE6DDRD2 | |
| SCHEMBL9040403 | 0.88 | PPARG (0.50) | PPARGAGTR1AGTR2PDE6DDRD2 | |
| SCHEMBL9040419 | 0.87 | HDAC1 (0.52) | TNFHDAC1HDAC6GALR3NR2F2 | |
| SCHEMBL9042383 | 0.87 | PPARG (0.60) | RAB9APPARGAGTR1AGTR2EDNRA | |
| SCHEMBL9040258 | 0.86 | SMN1; SMN2 (0.51) | PPARGAGTR1AGTR2 | |
| SCHEMBL9041999 | 0.86 | PDE6D (0.56) | PPARGPDE6DDRD2TBXA2R | |
| SCHEMBL9041160 | 0.86 | HDAC1 (0.58) | HDAC1HDAC6GRM2PPARGAGTR1 | |
| SCHEMBL9042664 | 0.86 | ALDH1A1 (0.71) | RAB9APDE6DDRD2TBXA2R | |
| SCHEMBL9041506 | 0.85 | PPARG (0.73) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |