Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 5/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.46 |
| ▸ | RELA | Q04206 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 5/20 | 0.40 |
| ▸ | CCKAR | P32238 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19224503 | 0.82 | NFKB1 (0.51) | NFKB1NFKB2RELACCKBRCCKAR | |
| SCHEMBL19207684 | 0.82 | NFKB1 (0.51) | NFKB1NFKB2RELACCKBRCCKAR | |
| SCHEMBL9040407 | 0.79 | CCKBR (0.44) | CCKBRCCKARNPSR1GAA | |
| SCHEMBL10498972 | 0.78 | LMNA (0.49) | LMNASMN1; SMN2CCKBRCCKARNPSR1 | |
| SCHEMBL8881603 | 0.78 | LMNA (0.49) | LMNASMN1; SMN2CCKBRCCKARNPSR1 | |
| SCHEMBL7421691 | 0.78 | CCKBR (0.51) | CCKBR | |
| SCHEMBL9230332 | 0.76 | CCKBR (0.38) | LMNASMN1; SMN2CCKBRCCKARNPSR1 | |
| SCHEMBL9226683 | 0.76 | LMNA (0.36) | LMNASMN1; SMN2CCKBRCCKARNPSR1 | |
| SCHEMBL7568437 | 0.76 | CCKBR (0.46) | CCKBRCCKAR | |
| SCHEMBL10499355 | 0.76 | CCKBR (0.46) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119955-A2 | 3-(5-Aminopentyl)-amino-1-benzazepin-2-one-1-alcanoic acids, process for their preparation, their pharmaceutical preparation as well as their therapeutic use | CIBA-GEIGY AG (CH) | 1984-09-26 | — | — | EP | disclosed |