SCHEMBL369310

SCHEMBL369310

O=C1NC(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c21

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
UCHL1 P09936 1/20 0.43
UCHL3 P15374 1/20 0.43
ECE1 P42892 1/20 0.43
MUS81 Q96NY9 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
PPOX P50336 1/20 0.39
CES1 P23141 9/20 0.36
DNMT1 P26358 1/20 0.34
PTGS2 P35354 1/20 0.33
GSK3B P49841 1/20 0.30
GAPDH P04406 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29414113 1.00 UCHL1 (0.43) UCHL1UCHL3ECE1MUS81ALDH1A1
SCHEMBL29202777 0.97 UCHL1 (0.41) UCHL1UCHL3ECE1MUS81ALDH1A1
Ethylene SCHEMBL16860555 0.94 UCHL1 (0.39) UCHL1UCHL3ECE1MUS81ALDH1A1
Ethane SCHEMBL29094893 0.94 UCHL1 (0.39) UCHL1UCHL3ECE1MUS81ALDH1A1
SCHEMBL13578741 0.84 PPOX (0.37) UCHL1UCHL3ECE1MUS81ALDH1A1
SCHEMBL3143690 0.81 UCHL1 (0.35) UCHL1UCHL3ECE1MUS81ALDH1A1
SCHEMBL9040639 0.79 ALDH1A1 (0.40) ALDH1A1TSHRPPOXCES1DNMT1
SCHEMBL3685169 0.79 PPOX (0.31) PPOX
SCHEMBL11411965 0.79 UCHL1 (0.33) UCHL1UCHL3ECE1MUS81ALDH1A1
SCHEMBL9154113 0.77 UCHL1 (0.32) UCHL1UCHL3ECE1MUS81ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 863 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12365678-B2 Pharmaceutical process for the preparation of 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-((R)-S-methylsulfonimidoyl) cyclopropyl]pyrimidin-2-yl}-1H-pyrrolo[2,3-b] pyridine and intermediates ASTRAZENECA AB (SE) 2025-07-22 US claimed
CN-119534412-A Method for rapidly detecting out-of-standard methanol in gasoline on site 福建师范大学 2025-02-28 CN claimed
US-20250002522-A1 OLIGOSACCHARIDE COMPOUNDS AND COMPLEXES CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2025-01-02 US claimed
CN-118414345-A Oligosaccharide compounds and complexes 生物技术公司 2024-07-30 CN claimed
EP-4402150-A1 OLIGOSACCHARIDE COMPOUNDS AND COMPLEXES BioNTech SE (DE) 2024-07-24 EP claimed
CN-113195728-B Pharmaceutical process and intermediates 阿斯利康(瑞典)有限公司 2024-07-16 CN claimed
EP-4286394-A1 OLIGOSACCHARIDE COMPOUNDS AND COMPLEXES BioNTech SE (DE) 2023-12-06 EP claimed
CN-115417849-B Method for catalytic synthesis of 3-isochromone 河南省化工研究所有限责任公司 2023-09-26 CN claimed
CN-116640066-A Method for synthesizing alkyl unnatural amino acid derivative by photocatalysis 大连理工大学 2023-08-25 CN claimed
CN-116601163-A Protected disaccharides, methods for their preparation, their use in the synthesis of zwitterionic oligosaccharides and conjugates thereof 巴斯德研究所 2023-08-15 CN claimed
US-4400509-A WITH HEXAMETHYLDISILANE WITH AN ORGANONITROGEN CATALYST GIST-BROCADES N.V. (NL) 1983-08-23 US claimed
EP-0043630-A2 Improved process for the silylation of organic compounds with 1,1,1-trimethyl-N-(trimethylsilyl)silanamine by means of catalysis with certain nitrogen containing compounds GIST-BROCADES N.V. (NL) 1982-01-13 EP claimed
EP-0003258-B1 PREPARATION OF N-CHLOROIMIDES AND A NOVEL N-CHLOROIMIDE ELI LILLY AND COMPANY (US) 1982-01-13 EP claimed
US-4273674-A HALOGENATED PHTHALIMIDES GENERAL ELECTRIC COMPANY (US) 1981-06-16 US claimed
US-4256507-A FLAVANTHRONE, PYRANTHRONE, INDANTHRONE, INDIGO, QUINACRIDONE, PERYLENE DIANHYDRIDE OR DIIMIDE PIGMENTS SUBSTITUTED WITH PHTHALIMIDO-METHYL GROUPS BASF AKTIENGESELLSCHAFT (DE) 1981-03-17 US claimed
EP-0014458-A1 Pigment preparations for lacquers and printing dyes BASF Aktiengesellschaft (DE) 1980-08-20 EP claimed
US-4208489-A AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-06-17 US claimed
US-4204428-A Thermal detection system for failure in electrical apparatus and thermal detecting paint compositions GENERAL ELECTRIC COMPANY (US) 1980-05-27 US claimed
EP-0003258-A1 Preparation of N-chloroimides and a novel N-chloroimide ELI LILLY AND COMPANY (US) 1979-08-08 EP claimed
US-4035383-A Eutectic process for preparing polychloro copper phthalocyanine E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-07-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12365678-B2 Pharmaceutical process for the preparation of 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-((R)-S-methylsulfonimidoyl) cyclopropyl]pyrimidin-2-yl}-1H-pyrrolo[2,3-b] pyridine and intermediates TPMT, CYP3A7, HTR7 UCHL1 2911/4885UCHL3 2853/4885ECE1 4070/4885
US-20250002522-A1 OLIGOSACCHARIDE COMPOUNDS AND COMPLEXES OSTC, FUT6, MAN2B2 UCHL1 4128/4885UCHL3 4146/4885ECE1 3104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.