Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904131 | 0.74 | GPR119 (0.49) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL10068005 | 0.74 | GPR119 (0.49) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL10067591 | 0.72 | PTGS2 (0.40) | PTGS2PTGS1GCKMMP2MMP3 | |
| SCHEMBL903948 | 0.69 | SLC9A3 (0.43) | PTGS2PTGS1SLC9A3 | |
| SCHEMBL9034923 | 0.69 | PTGS2 (0.55) | PTGS2PTGS1GCKMMP1MMP2 | |
| SCHEMBL387949 | 0.67 | GPR119 (0.46) | PTGS2PTGS1GCKTGFBR1MMP1 | |
| SCHEMBL8941654 | 0.67 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL10300269 | 0.66 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL7677302 | 0.66 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL26064614 | 0.66 | ENPP2 (0.43) | PTGS2PTGS1GCKSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041158-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-04-05 | — | — | WO | disclosed |