Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958473 | 0.87 | CNR1 (0.58) | CNR1ACHECNR2CYP1A2CYP2D6 | |
| SCHEMBL9041922 | 0.81 | ALDH1A1 (0.51) | P2RX4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9980879 | 0.79 | PTGER4 (0.58) | P2RX4CNR1ACHECNR2CYP1A2 | |
| SCHEMBL16691703 | 0.79 | PTGER4 (0.58) | P2RX4CNR1ALDH1A1SLC16A3PTGER4 | |
| SCHEMBL9042123 | 0.77 | CASP3 (0.41) | ALDH1A1KDM4ENPC1MAPTHPGD | |
| SCHEMBL1898956 | 0.77 | CNR1 (0.58) | P2RX4CNR1ACHECNR2CYP1A2 | |
| SCHEMBL9231345 | 0.77 | CNR1 (0.58) | P2RX4CNR1ACHECNR2CYP1A2 | |
| SCHEMBL18131335 | 0.76 | KDM4E (0.47) | CNR1ACHECNR2CYP1A2CYP2D6 | |
| SCHEMBL29459606 | 0.76 | TDP1 (0.50) | CNR1ACHECNR2CYP1A2CYP2D6 | |
| SCHEMBL17039004 | 0.76 | TDP1 (0.50) | CNR1ACHECNR2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613470-B1 | NOVEL 4-CINNOLINONE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPY | PF MEDICAMENT (FR) | 1996-01-10 | — | — | EP | claimed |