Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14216404 | 0.86 | SLC9A1 (0.43) | ALDH1A1MAPTPDE4APDE4BPDE4C | |
| SCHEMBL9882815 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPTPDE4APDE4BPDE4C | |
| SCHEMBL9041703 | 0.81 | P2RX4 (0.54) | ALDH1A1MAPTPDE4APDE4BPDE4C | |
| SCHEMBL9043723 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTPDE4APDE4BPDE4C | |
| SCHEMBL9042310 | 0.80 | KDM4C (0.43) | ALDH1A1MAPTHSD17B10KDM4EMEN1 | |
| SCHEMBL9042123 | 0.80 | CASP3 (0.41) | ALDH1A1MAPTHSD17B10KDM4EMEN1 | |
| SCHEMBL9042883 | 0.78 | LMNA (0.42) | ALDH1A1MAPTKDM4EMEN1HTT | |
| SCHEMBL9042400 | 0.78 | MAPK8 (0.44) | CDK1 | |
| SCHEMBL9043059 | 0.78 | MAPK8 (0.53) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL9041998 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613470-B1 | NOVEL 4-CINNOLINONE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPY | PF MEDICAMENT (FR) | 1996-01-10 | — | — | EP | claimed |