Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3622654 | 0.87 | MAPK1 (0.46) | CASP3MAPK1GAAPLK1APOBEC3G | |
| SCHEMBL9041922 | 0.80 | ALDH1A1 (0.51) | MAPK1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7298497 | 0.78 | MEN1 (0.46) | CASP3MAPK1NPC1ALDH1A1KDM4E | |
| SCHEMBL9041703 | 0.77 | P2RX4 (0.54) | MAPK1NPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL8875584 | 0.75 | ELANE (0.51) | — | |
| SCHEMBL18967143 | 0.74 | KMT2A (0.39) | CASP3GAAPLK1APOBEC3GALDH1A1 | |
| SCHEMBL12253484 | 0.74 | GLS (0.58) | CASP3APOBEC3GALDH1A1KDM4EHPGD | |
| SCHEMBL6096584 | 0.73 | MEN1 (0.39) | CASP3GAAPLK1APOBEC3GALDH1A1 | |
| SCHEMBL6946908 | 0.73 | CYP1A2 (0.52) | MAPK1NPC1KDM4EMEN1KMT2A | |
| SCHEMBL18967496 | 0.73 | PARP1 (0.37) | CASP3ALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613470-B1 | NOVEL 4-CINNOLINONE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPY | PF MEDICAMENT (FR) | 1996-01-10 | — | — | EP | claimed |