Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 12/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040489 | 0.90 | CCKBR (0.47) | CCKBRBRD4HDAC3HDAC1HDAC8 | |
| SCHEMBL9039747 | 0.89 | CCKBR (0.51) | CCKBRHDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL9039585 | 0.88 | CCKBR (0.61) | CCKBR | |
| SCHEMBL9039031 | 0.88 | CCKBR (0.50) | CCKBRTP53POLB | |
| SCHEMBL9042659 | 0.87 | CCKBR (0.51) | CCKBRTP53POLB | |
| SCHEMBL9040311 | 0.85 | CCKBR (0.51) | CCKBR | |
| SCHEMBL9041035 | 0.84 | CCKBR (0.51) | CCKBR | |
| SCHEMBL9040881 | 0.83 | CCKBR (0.51) | CCKBRTP53POLB | |
| SCHEMBL9041225 | 0.83 | CCKBR (0.71) | CCKBRTP53POLB | |
| SCHEMBL9040062 | 0.83 | CCKBR (0.62) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703222-A1 | 3-AMINOAZEPINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-03-27 | — | — | EP | disclosed |