Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902201 | 0.78 | KDM1A (0.50) | KDM1APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL21276900 | 0.69 | SIRT1 (0.45) | KDM4EALDH1A1HPGDMAOASMN1; SMN2 | |
| SCHEMBL23172252 | 0.68 | KDM4E (0.56) | KDM1APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL17423359 | 0.67 | KDM4E (0.50) | KDM1APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7869236 | 0.66 | KDM1A (0.48) | KDM1APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL4894495 | 0.64 | KDM4E (0.56) | KDM1APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL8209747 | 0.63 | KDM1A (0.46) | KDM1APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7875736 | 0.63 | ACHE (0.47) | KDM1APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL5705500 | 0.63 | KDM4E (0.46) | KDM1APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7875759 | 0.63 | KDM1A (0.46) | KDM1APOLBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012042265-A1 | NOVEL ACRIDINE DERIVATIVES | PHARMINOX LIMITED (GB) | 2012-04-05 | — | — | WO | disclosed |