Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044253 | 0.86 | ALDH1A1 (0.38) | ALDH1A1KDM4EGLAPTGER4PTGER3 | |
| SCHEMBL9042766 | 0.79 | PTPRC (0.47) | MAOBL3MBTL1TSHRLMNAMAPT | |
| SCHEMBL12419176 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4EGLAMAOBL3MBTL1 | |
| SCHEMBL9349875 | 0.77 | CA12 (0.35) | ALDH1A1KDM4EGLAL3MBTL1LMNA | |
| SCHEMBL9042817 | 0.77 | L3MBTL1 (0.40) | ALDH1A1PTGDR2MAOBL3MBTL1TSHR | |
| SCHEMBL9042022 | 0.77 | PTPRC (0.37) | ALDH1A1KDM4EGLAPTGER4PTGER3 | |
| SCHEMBL9042223 | 0.76 | FFAR1 (0.39) | ALDH1A1PTGDR2MAOBL3MBTL1LMNA | |
| SCHEMBL9043779 | 0.75 | ALDH1A1 (0.33) | ALDH1A1KDM4EGLAPTGDR2MAOB | |
| SCHEMBL9043071 | 0.74 | PPARA (0.34) | ALDH1A1KDM4EPTGER4PTGER3PTGER2 | |
| SCHEMBL9044386 | 0.74 | L3MBTL1 (0.39) | ALDH1A1MAOBL3MBTL1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |