Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10728827 | 0.81 | GABRA5 (0.49) | GABRA5ADORA3KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3590577 | 0.81 | MBD2 (0.47) | GABRA5KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9043651 | 0.80 | GABRA5 (0.49) | GABRA5ADORA3KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11403965 | 0.75 | ADORA3 (0.46) | GABRA5ADORA3KDM4EALDH1A1GAA | |
| SCHEMBL11402491 | 0.69 | ADORA3 (0.60) | GABRA5ADORA3KDM4EALDH1A1GAA | |
| SCHEMBL28858361 | 0.69 | ALDH1A1 (0.35) | KDM4EALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL29993425 | 0.69 | ALDH1A1 (0.35) | KDM4EALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL31093975 | 0.68 | GABRA5 (0.55) | GABRA5ADORA3KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1278798 | 0.68 | GABRA5 (0.55) | GABRA5ADORA3KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25857423 | 0.67 | TOP2A (0.51) | KDM4EALDH1A1SMN1; SMN2GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-A1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022865-A1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |