Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040723 | 0.89 | CNR2 (0.56) | CNR2EPHX2LMNACNR1FAAH | |
| SCHEMBL9043610 | 0.88 | CNR2 (0.38) | CNR2EPHX2P2RX7CNR1ALDH1A1 | |
| SCHEMBL9044863 | 0.80 | EPHX2 (0.52) | CNR2EPHX2LMNAROCK2MEN1 | |
| SCHEMBL9044489 | 0.76 | CNR2 (0.52) | CNR2EPHX2CNR1FAAHALDH1A1 | |
| SCHEMBL9041625 | 0.74 | RAB9A (0.49) | CNR2EPHX2CNR1ALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL9040759 | 0.74 | LMNA (0.43) | LMNAALDH1A1ROCK2MEN1KMT2A | |
| SCHEMBL9042891 | 0.73 | LMNA (0.45) | LMNAALDH1A1NPSR1ROCK2MEN1 | |
| SCHEMBL9042416 | 0.68 | HPGD (0.49) | LMNAFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL9043728 | 0.66 | HSD11B1 (0.41) | CNR2LMNAFAAHMEN1KMT2A | |
| SCHEMBL30772293 | 0.65 | KDM4E (0.49) | LMNAALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6073010-A | — | — | None | — | — | JP | disclosed |
| EP-0578419-B1 | Pyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1996-09-04 | — | — | EP | disclosed |
| JP-H0673010-A | PYRIDINE DERIVATIVE | KYOWA HAKKO KOGYO CO LTD | 1994-03-15 | — | — | JP | disclosed |
| EP-0578419-A1 | Pyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-01-12 | — | — | EP | disclosed |