Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043610 | 0.88 | CNR2 (0.38) | CNR2TSHRPABPC1EPHX2KDM4E | |
| SCHEMBL9040723 | 0.87 | CNR2 (0.56) | CNR2TSHRPABPC1EPHX2ALDH1A1 | |
| SCHEMBL9043728 | 0.81 | HSD11B1 (0.41) | CNR2HTTFAAH | |
| SCHEMBL9044359 | 0.76 | NPC1 (0.47) | KDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL9044341 | 0.76 | CNR2 (0.42) | CNR2TSHREPHX2ALDH1A1NPSR1 | |
| SCHEMBL9041316 | 0.74 | EPHX1 (0.45) | EPHX2KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9520932 | 0.71 | ALDH1A1 (0.49) | CNR2TSHREPHX2KDM4EHSD17B10 | |
| SCHEMBL2917775 | 0.70 | CNR2 (1.00) | CNR2TSHREPHX2KDM4EHSD17B10 | |
| SCHEMBL16872821 | 0.69 | FAAH (0.71) | CNR2TSHRPABPC1EPHX2KDM4E | |
| SCHEMBL28444022 | 0.68 | CNR2 (0.70) | CNR2TSHRPABPC1EPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578419-B1 | Pyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1996-09-04 | — | — | EP | disclosed |
| EP-0578419-A1 | Pyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-01-12 | — | — | EP | disclosed |