Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27309786 | 1.00 | RAD52 (0.31) | RAD52MAPTBLMALDH1A1LMNA | |
| SCHEMBL7669287 | 0.85 | SMN1; SMN2 (0.33) | RAD52MAPTBLMALDH1A1LMNA | |
| SCHEMBL8064684 | 0.85 | OXTR (0.44) | MAPTMEN1KMT2A | |
| SCHEMBL7658017 | 0.84 | ALDH1A1 (0.34) | RAD52MAPTBLMALDH1A1LMNA | |
| SCHEMBL7752451 | 0.84 | ALDH1A1 (0.34) | RAD52MAPTBLMALDH1A1LMNA | |
| SCHEMBL9046364 | 0.80 | ALDH1A1 (0.36) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL7658367 | 0.79 | MMP2 (0.35) | RAD52MAPTBLMALDH1A1LMNA | |
| SCHEMBL7668595 | 0.77 | GAA (0.40) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL27315098 | 0.76 | LIPE (0.45) | MAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL9046781 | 0.76 | LIPE (0.45) | MAPTALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366085-B1 | Tetrahydropyrimidines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5084459-A | Insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |