Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9036301 | 0.99 | ADRA1A (0.48) | ADRA1ADRD4HTR2A | |
| SCHEMBL9035359 | 0.86 | ADRA1A (0.52) | ADRA1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL9036115 | 0.85 | ADRA1A (0.51) | ADRA1ADRD4HTR2A | |
| SCHEMBL9041980 | 0.81 | ADRA1A (0.56) | ADRA1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL9037035 | 0.81 | ADRA1A (0.55) | ADRA1ADRD4HTR2A | |
| SCHEMBL7828641 | 0.72 | HTR2A (0.54) | ADRA1ADRD4HTR2A | |
| SCHEMBL7823924 | 0.72 | HTR2A (0.58) | ADRA1ADRD4HTR2A | |
| SCHEMBL7824411 | 0.71 | ADRA1A (0.70) | ADRA1ADRD4HTR2A | |
| Fumaric Acid SCHEMBL7835323 | 0.70 | ADRA1A (0.54) | ADRA1ADRD4HTR2A | |
| SCHEMBL4442569 | 0.70 | HTR1A (0.65) | ADRA1ADRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225412-A | Antipsychotic | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-06 | — | — | US | claimed |
| EP-0511610-B1 | Benzisothiazole- and benzisoxazole-3-carboxamides, a process for their preparation and their use as antipsychotic medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0511610-A1 | Benzisothiazole- and benzisoxazole-3-carboxamides, a process for their preparation and their use as antipsychotic medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-11-04 | — | — | EP | disclosed |