Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | BID | P55957 | 7/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.56 |
| ▸ | BAK1 | Q16611 | 6/20 | 0.56 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.56 |
| ▸ | EP300 | Q09472 | 3/20 | 0.56 |
| ▸ | KAT5 | Q92993 | 3/20 | 0.56 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.56 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.56 |
| ▸ | SOX18 | P35713 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308264 | 0.83 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29919590 | 0.82 | BID (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3954149 | 0.82 | BID (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11571511 | 0.82 | CA12 (0.64) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3886524 | 0.80 | AKR1B1 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28148009 | 0.80 | FOLH1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27961262 | 0.80 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7781034 | 0.78 | MMP2 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18280304 | 0.78 | L3MBTL1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27860026 | 0.78 | ALDH1A1 (0.39) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104853757-A | 4-heteroaryl substituted benzoic acid compounds as ROR gamma T inhibitors and uses thereof | MERCK SHARP & DOHME | 2015-08-19 | — | — | CN | disclosed |
| EP-0700907-A1 | Process for producing pyrimidine derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-03-13 | — | — | EP | disclosed |