Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046306 | 0.88 | ALOX15 (0.42) | TP53ALOX15POLBMEN1KMT2A | |
| SCHEMBL9044691 | 0.86 | POLB (0.38) | TP53S1PR5S1PR1RAB9APOLB | |
| SCHEMBL9044569 | 0.83 | PYGL (0.35) | ALOX15POLBMEN1KMT2AKDM4E | |
| SCHEMBL6771023 | 0.83 | TP53 (0.43) | TP53S1PR5S1PR1ALOX15RAB9A | |
| SCHEMBL6771445 | 0.80 | TP53 (0.40) | TP53S1PR5S1PR1ALOX15RAB9A | |
| SCHEMBL9044742 | 0.80 | S1PR5 (0.46) | S1PR5S1PR1S1PR3 | |
| SCHEMBL9044861 | 0.77 | ALOX15 (0.41) | TP53ALOX15POLBMEN1KMT2A | |
| SCHEMBL9045709 | 0.76 | S1PR5 (0.49) | S1PR5S1PR1KMT2AALDH1A1 | |
| SCHEMBL9044507 | 0.74 | S1PR5 (0.46) | S1PR5S1PR1S1PR3 | |
| SCHEMBL9045439 | 0.73 | NPC1 (0.39) | TP53ALOX15RAB9APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706527-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AG (DE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001358-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-12 | — | — | WO | disclosed |