Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044861 | 0.89 | ALOX15 (0.41) | ALOX15MEN1KMT2APOLBOPRM1 | |
| SCHEMBL9044569 | 0.88 | PYGL (0.35) | ALOX15MEN1KMT2APOLBLMNA | |
| SCHEMBL9044843 | 0.88 | TP53 (0.40) | ALOX15MEN1KMT2APOLBTP53 | |
| SCHEMBL9045439 | 0.85 | NPC1 (0.39) | ALOX15MEN1KMT2APOLBOPRM1 | |
| SCHEMBL6762557 | 0.81 | ALOX15 (0.42) | ALOX15MEN1KMT2APOLBOPRM1 | |
| SCHEMBL6850976 | 0.79 | ALOX15 (0.40) | ALOX15MEN1KMT2APOLBOPRM1 | |
| SCHEMBL6771158 | 0.77 | ALOX15 (0.40) | ALOX15OPRM1TP53 | |
| SCHEMBL9045718 | 0.75 | ALDH1A1 (0.58) | MEN1KMT2APOLBLMNA | |
| SCHEMBL9045046 | 0.74 | KMT2A (0.45) | KMT2APOLBP2RX7 | |
| SCHEMBL9045049 | 0.74 | CYP3A4 (0.37) | ALOX15MEN1KMT2AOPRM1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706527-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AG (DE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001358-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-12 | — | — | WO | disclosed |