Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466166 | 0.78 | CYP1A2 (0.39) | KDM4ESMN1; SMN2CYP1A2ALDH1A1MAPT | |
| SCHEMBL6469855 | 0.76 | KDM4E (0.49) | KDM4ESMN1; SMN2HSD17B10TP53CYP1A2 | |
| SCHEMBL8462928 | 0.76 | GPR84 (0.35) | ALDH1A1GPR84HTT | |
| SCHEMBL9044423 | 0.74 | SMN1; SMN2 (0.36) | KDM4ESMN1; SMN2HSD17B10TP53CYP1A2 | |
| SCHEMBL7020390 | 0.73 | MEN1 (0.40) | KDM4ESMN1; SMN2HSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL8466902 | 0.73 | GAA (0.38) | KDM4ESMN1; SMN2CYP1A2ALDH1A1HPGD | |
| SCHEMBL9046316 | 0.73 | KDM4E (0.35) | KDM4ESMN1; SMN2HSD17B10TP53CYP1A2 | |
| SCHEMBL1338698 | 0.73 | SMN1; SMN2 (0.40) | KDM4ESMN1; SMN2HSD17B10TP53CYP1A2 | |
| SCHEMBL9292094 | 0.70 | ALDH1A1 (0.43) | KDM4EHSD17B10CYP1A2ALDH1A1MAPT | |
| SCHEMBL9044862 | 0.70 | PDE4D (0.51) | KDM4ESMN1; SMN2HSD17B10TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749433-A1 | (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY | ZENECA LIMITED (GB) | 1996-12-27 | — | — | EP | disclosed |