Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | FHIT | P49789 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046330 | 0.84 | PDE4D (0.33) | PDE4D | |
| SCHEMBL9044878 | 0.82 | HPGDS (0.47) | KDM4EMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7020400 | 0.75 | ALDH1A1 (0.42) | PDE4DKDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL8466166 | 0.70 | CYP1A2 (0.39) | KDM4EMAPTPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL9044890 | 0.70 | KDM4E (0.36) | PDE4DKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL353564 | 0.70 | PDE4D (1.00) | PDE4DKDM4EMAPTPOLBKMT2A | |
| SCHEMBL8466902 | 0.68 | GAA (0.38) | KDM4EPOLBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7019281 | 0.68 | RAB9A (0.49) | KDM4EMAPTPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL21130898 | 0.67 | PDE4D (0.73) | PDE4DKDM4EMAPTPOLBKMT2A | |
| SCHEMBL7519069 | 0.67 | PDE4D (0.73) | PDE4DKDM4EMAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749433-A1 | (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY | ZENECA LIMITED (GB) | 1996-12-27 | — | — | EP | disclosed |