SCHEMBL9045152

SCHEMBL9045152

Cc1[nH]c(SCCC=C(F)F)nc1C(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8463176 0.82 MCL1 (0.35) GPR84
SCHEMBL8462928 0.81 GPR84 (0.35) GPR84
SCHEMBL9044890 0.72 KDM4E (0.36) GPR84
SCHEMBL9046224 0.70
SCHEMBL8466514 0.69 GPR84 (0.31) GPR84
SCHEMBL8752059 0.68 KDM6B (0.42)
SCHEMBL7020173 0.67 SMN1; SMN2 (0.62)
SCHEMBL8752020 0.64 POLB (0.63) GPR84
SCHEMBL8752033 0.63 PKM (0.58) GPR84
SCHEMBL8751991 0.63 MEN1 (0.52) GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0749433-A1 (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY ZENECA LIMITED (GB) 1996-12-27 EP disclosed