SCHEMBL904516

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL904565	0.89	KMT2A (0.42)	PRSS1TPSAB1TPSD1TPSG1F2
	SCHEMBL904606	0.85	HPGD (0.46)	CNR2ADORA2A
	SCHEMBL904820	0.84	HPGD (0.47)	CNR2ADORA2A
	SCHEMBL904611	0.82	FAAH (0.46)	PRSS1TPSAB1TPSD1TPSG1F2
	SCHEMBL904636	0.81	PRSS1 (0.55)	PRSS1TPSAB1TPSD1TPSG1F2
	SCHEMBL904413	0.80	TPSAB1 (0.45)	PRSS1TPSAB1TPSD1TPSG1F2
	SCHEMBL904430	0.80	TPSAB1 (0.48)	PRSS1TPSAB1TPSD1TPSG1F2
	SCHEMBL904547	0.80	TPSAB1 (0.42)	PRSS1TPSAB1TPSD1TPSG1F2
	SCHEMBL904527	0.79	DPP4 (0.43)	P2RY12
	SCHEMBL904539	0.78	NAMPT (0.46)	PRSS1TPSAB1TPSD1TPSG1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.