Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057272 | 0.88 | CA2 (0.39) | GABRA1GABRB2CA2 | |
| SCHEMBL9047077 | 0.83 | GABRA1 (0.43) | GABRA1GABRB2CA2 | |
| SCHEMBL9046228 | 0.81 | GABRA1 (0.33) | GABRA1GABRB2CA2 | |
| SCHEMBL9047171 | 0.81 | TAAR1 (0.35) | GABRA1GABRB2CA2 | |
| SCHEMBL9046312 | 0.80 | CA2 (0.35) | GABRA1GABRB2CA2 | |
| SCHEMBL9044851 | 0.80 | ALDH1A1 (0.40) | — | |
| SCHEMBL9048354 | 0.79 | GABRA1 (0.36) | GABRA1GABRB2CA2 | |
| SCHEMBL9058555 | 0.78 | GABRA1 (0.40) | GABRA1GABRB2CA2 | |
| SCHEMBL9049966 | 0.78 | GABRA1 (0.32) | GABRA1GABRB2CA2 | |
| SCHEMBL9047068 | 0.78 | HTR1A (0.36) | GABRA1GABRB2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | disclosed |