Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GMNN | O75496 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27742463 | 0.87 | CYP1A2 (0.42) | CYP1A2LMNAMAPK1MAPTGMNN | |
| SCHEMBL28422012 | 0.87 | GPR84 (0.44) | CYP1A2LMNAMAPK1MAPTGMNN | |
| SCHEMBL15445475 | 0.85 | CYP1A2 (0.41) | CYP1A2LMNAMAPK1MAPTGMNN | |
| SCHEMBL15945368 | 0.85 | CYP1A2 (0.41) | CYP1A2LMNAMAPK1MAPTGMNN | |
| SCHEMBL28427449 | 0.84 | GPR84 (0.54) | CYP1A2LMNAMAPK1MAPTGMNN | |
| SCHEMBL28415473 | 0.83 | GPR84 (0.62) | CYP1A2LMNAMAPK1MAPTGMNN | |
| SCHEMBL18485858 | 0.82 | MMP1 (0.50) | CYP1A2LMNAMAPK1MAPTGMNN | |
| SCHEMBL28420916 | 0.82 | GPR84 (0.65) | CYP1A2LMNAMAPK1MAPTGMNN | |
| SCHEMBL28415643 | 0.82 | GPR84 (0.65) | CYP1A2LMNAMAPK1MAPTGMNN | |
| SCHEMBL28891565 | 0.82 | GPR84 (0.65) | CYP1A2LMNAMAPK1MAPTGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011133436-A1 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2011-10-27 | — | — | WO | claimed |
| US-20110027336-A1 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-02-03 | — | — | US | claimed |
| WO-2011160102-A2 | SYSTEM AND METHOD FOR DETERMINING STRUCTURAL CHARACTERISTICS OF AN OBJECT | PERIMETRICS, LLC (US) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011133436-A1 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2011-10-27 | — | — | WO | disclosed |
| US-8025502-B2 | Light guide for dentistry applications | DISCUS DENTAL, LLC (US) | 2011-09-27 | — | — | US | disclosed |
| US-20110027336-A1 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110027336-A1 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME | LDHA, LDHB, CA1 | CYP1A2 4312/4885LMNA 2203/4885MAPK1 1734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.