Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433221 | 0.90 | LMNA (0.59) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9043950 | 0.89 | LMNA (0.49) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9043035 | 0.86 | KMT2A (0.62) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9046461 | 0.86 | LMNA (0.52) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10884458 | 0.83 | KDM4E (0.54) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL9047457 | 0.82 | LMNA (0.49) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9433406 | 0.78 | LMNA (0.62) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9046854 | 0.76 | LMNA (0.45) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9046101 | 0.76 | ALDH1A1 (0.47) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7819707 | 0.76 | MEN1 (0.78) | LMNAMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422485-B1 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1996-04-03 | — | — | EP | disclosed |
| EP-0422485-A2 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |