Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPD | P32754 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046534 | 0.89 | NOTUM (0.41) | NOTUMKDM4ESMN1; SMN2POLBMEN1 | |
| SCHEMBL9046000 | 0.86 | KDM4E (0.43) | NOTUMKDM4ESMN1; SMN2POLBMEN1 | |
| SCHEMBL9044837 | 0.77 | GLA (0.40) | NOTUMKDM4ESMN1; SMN2MEN1KMT2A | |
| Bicarbonate SCHEMBL9046548 | 0.75 | PTGS1 (0.43) | NOTUMKDM4ESMN1; SMN2POLBMEN1 | |
| SCHEMBL7123595 | 0.70 | ALDH1A1 (0.41) | NOTUMKDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL12984605 | 0.69 | ALDH1A1 (0.63) | KDM4EPOLBMEN1KMT2AHSD17B10 | |
| Bicarbonate SCHEMBL9046542 | 0.67 | PTGS1 (0.41) | NOTUMPOLBMEN1KMT2APTGS1 | |
| SCHEMBL13802514 | 0.65 | ALDH1A1 (0.56) | KDM4EPOLBMAPTHSD17B10ALDH1A1 | |
| SCHEMBL11625313 | 0.65 | NOTUM (0.67) | NOTUMKDM4ESMN1; SMN2POLBMEN1 | |
| SCHEMBL5824022 | 0.65 | HPGD (0.41) | KDM4ESMN1; SMN2MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422485-B1 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1996-04-03 | — | — | EP | disclosed |
| US-5300643-A | Viricides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| US-5217972-A | QUINOLONECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIVIRAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | disclosed |
| EP-0422485-A2 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |