SCHEMBL904731

SCHEMBL904731

CC(C)(CCOCC1CO1)O[SiH3]

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 6/20 0.46
TDP1 Q9NUW8 1/20 0.46
TP53 P04637 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CYP1A2 P05177 1/20 0.34
PPARG P37231 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125940 0.89 TSHR (0.57) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL153464 0.89 TSHR (0.62) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL17710340 0.88 TSHR (0.60) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL9133579 0.87 ALDH1A1 (0.55) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL24177617 0.84 ALDH1A1 (0.52) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL4268958 0.81 TSHR (0.64) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL5268219 0.81 TSHR (0.54) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL4298953 0.80 TSHR (0.58) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL1995127 0.79 SMN1; SMN2 (0.50) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL614218 0.79 TSHR (0.57) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026105755-A1 ANTITHROMBOTIC COATING MATERIAL, MEDICAL DEVICE, RESEARCH INSTRUMENT, METHODS FOR PRODUCING MEDICAL DEVICE AND RESEARCH INSTRUMENT, AND ADSORPTION SUPPRESSION METHOD JSR株式会社 2026-05-21 WO disclosed
CN-115305097-A Liquid crystal aligning agent, liquid crystal alignment film and method for producing same, liquid crystal element, liquid crystal display device, and polymer JSR株式会社 2022-11-08 CN disclosed
US-10941323-B2 Composite of metal and resin ADVANCED TECHNOLOGIES, INC. (JP) 2021-03-09 US disclosed
CN-112210390-A Liquid crystal aligning agent, liquid crystal alignment film, method for producing liquid crystal alignment film, liquid crystal display element, polymer, and compound JSR株式会社 2021-01-12 CN disclosed
US-20200377767-A1 COMPOSITE OF METAL AND RESIN ADVANCED TECHNOLOGIES, INC. (JP) 2020-12-03 US disclosed
CN-107111191-B Liquid crystal aligning agent, liquid crystal alignment film, method for producing liquid crystal alignment film, liquid crystal display element, polymer, and compound JSR株式会社 2020-11-06 CN disclosed
CN-110997314-B Composite material of metal and resin 株式会社新技术研究所 2020-10-09 CN disclosed
EP-3663084-A1 COMPOSITE OF METAL AND RESIN Advanced Technologies, Inc. (JP) 2020-06-10 EP disclosed
CN-110997314-A Composite material of metal and resin 株式会社新技术研究所 2020-04-10 CN disclosed
CN-105567259-B Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display element, and polymer JSR株式会社 2020-03-13 CN disclosed
US-20080145436-A1 Aqueous phase dispersed in an oily phase, a silicone emulsifier, a hydrophilic acrylic polymers and 2-acrylamido-2-methylpropanesulfonic acid polymers, and a silicon-based filler L'OREAL (FR) 2008-06-19 US disclosed
US-20080108535-A1 COMPOSITION CONTAINING HOLLOW HEMISPHERICAL PARTICLES L'OREAL (FR) 2008-05-08 US disclosed
US-20080044365-A1 Concave or annular particles of silicone materials for increasing the sun protection factor of aqueous photoprotective compositions comprising same L'OREAL (FR) 2008-02-21 US disclosed
US-7276615-B2 Organofunctional surface-modified metal oxides WACKER CHEMIE AG (DE) 2007-10-02 US disclosed
US-20070154500-A1 COMPOSITION CONTAINING CONCAVE PARTICLES AND A DISPERSANT, PROCESSES AND USES L'OREAL (FR) 2007-07-05 US disclosed
US-20060293431-A1 Cosmetic composition comprising silicone particles L'OREAL S.A. (FR) 2006-12-28 US disclosed
US-20050220741-A1 Cosmetic composition comprising concave particles L'OREAL S.A. (FR) 2005-10-06 US disclosed
US-20050220740-A1 Cosmetic composition comprising concave particles L'OREAL S.A. (FR) 2005-10-06 US disclosed
US-20040220419-A1 Organofunctional surface-modified metal oxides WACKER-CHEMIE GMBH (DE) 2004-11-04 US disclosed
US-5093389-A Epoxy-Terminated Polysiloxane, Silanol-Terminated Polysiloxane Aminoxysilicon Compound TOSHIBA SILICONE CO., LTD. (JP) 1992-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080145436-A1 Aqueous phase dispersed in an oily phase, a silicone emulsifier, a hydrophilic acrylic polymers and 2-acrylamido-2-methylpropanesulfonic acid polymers, and a silicon-based filler CUTA, MPHOSPH6, ARID2 TSHR 4188/4885MAPK1 1553/4885SMN1; SMN2 452/4885
US-20080044365-A1 Concave or annular particles of silicone materials for increasing the sun protection factor of aqueous photoprotective compositions comprising same ERCC4, BRCA1, ERCC2 TSHR 3655/4885MAPK1 2643/4885SMN1; SMN2 3217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.