Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048106 | 0.82 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9051082 | 0.78 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2LMNAAKR1A1 | |
| SCHEMBL9047096 | 0.77 | KMT2A (0.55) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9057868 | 0.77 | KMT2A (0.49) | MEN1KMT2ALMNAAKR1B1PTGDR2 | |
| SCHEMBL9048800 | 0.75 | LMNA (0.51) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9046149 | 0.74 | AKR1B1 (0.59) | MEN1KMT2AMAPTAKR1A1AKR1B1 | |
| SCHEMBL11269563 | 0.73 | LMNA (0.62) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9050224 | 0.72 | LMNA (0.42) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9047397 | 0.72 | NR4A2 (0.48) | MEN1KMT2ASMN1; SMN2LMNAAKR1A1 | |
| SCHEMBL9050331 | 0.71 | PTGDR2 (0.42) | MEN1KMT2ATP53AKR1B1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456835-B1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN SEIYAKU KK (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5234928-A | Inhibit platelet aggregation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0456835-A1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |