Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | LTK | P29376 | 1/20 | 0.45 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047096 | 0.88 | KMT2A (0.55) | MEN1KMT2AAKR1A1AKR1B1LMNA | |
| SCHEMBL9046675 | 0.88 | SMN1; SMN2 (0.51) | NR4A2MEN1KMT2ASLC26A4POLB | |
| SCHEMBL9047449 | 0.78 | LMNA (0.52) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL10488016 | 0.78 | AKR1A1 (0.60) | MEN1KMT2AAKR1A1AKR1B1LMNA | |
| SCHEMBL11269563 | 0.76 | LMNA (0.62) | MEN1KMT2AAKR1A1AKR1B1LMNA | |
| SCHEMBL9051080 | 0.76 | LMNA (0.47) | MEN1KMT2AAKR1A1AKR1B1LMNA | |
| SCHEMBL9051076 | 0.75 | LMNA (0.46) | MEN1KMT2AAKR1A1AKR1B1POLB | |
| SCHEMBL9047901 | 0.74 | LMNA (0.52) | MEN1KMT2AAKR1A1AKR1B1POLB | |
| SCHEMBL9056716 | 0.73 | AKR1B1 (0.78) | MEN1KMT2AAKR1A1AKR1B1PTGDR2 | |
| SCHEMBL9048660 | 0.72 | AKR1A1 (0.49) | MEN1KMT2AAKR1A1AKR1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456835-B1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN SEIYAKU KK (JP) | 1996-05-15 | — | — | EP | claimed |
| EP-0456835-B1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN SEIYAKU KK (JP) | 1996-05-15 | — | — | EP | disclosed |