Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047060 | 0.92 | KMT2A (0.56) | MEN1KMT2APTGER1OPRM1TMEM97 | |
| SCHEMBL9046860 | 0.86 | MEN1 (0.53) | MEN1KMT2AOPRM1TMEM97SIGMAR1 | |
| SCHEMBL8828332 | 0.84 | OPRM1 (0.47) | PTGER1OPRM1TMEM97SIGMAR1MAPT | |
| SCHEMBL8828302 | 0.82 | LMNA (0.58) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8828260 | 0.79 | OPRM1 (0.47) | MEN1KMT2APTGER1OPRM1TMEM97 | |
| SCHEMBL8828430 | 0.77 | MAPT (0.59) | MEN1KMT2AOPRM1MAPTALDH1A1 | |
| SCHEMBL8828184 | 0.76 | OPRM1 (0.49) | MEN1KMT2AOPRM1TMEM97SIGMAR1 | |
| SCHEMBL10985999 | 0.76 | CYP3A4 (0.53) | MEN1KMT2AOPRM1TMEM97SIGMAR1 | |
| SCHEMBL9809676 | 0.75 | OPRM1 (0.58) | OPRM1TMEM97SIGMAR1MAPTOPRK1 | |
| SCHEMBL9425666 | 0.74 | MEN1 (0.70) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344577-B1 | Butenoic or propenoic acid derivatives | EISAI CO LTD (JP) | 1996-10-09 | — | — | EP | disclosed |
| EP-0344577-A2 | Butenoic or propenoic acid derivatives | Eisai Co., Ltd. (JP) | 1989-12-06 | — | — | EP | disclosed |