Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461433 | 0.83 | LMNA (0.43) | TSHRHTTL3MBTL1MAPK1LMNA | |
| SCHEMBL2130491 | 0.77 | ALDH1A1 (0.47) | HTTMAPK1LMNACES2CES1 | |
| SCHEMBL7496934 | 0.76 | ALDH1A1 (0.53) | TSHRMAPK1LMNACES2CES1 | |
| SCHEMBL16952696 | 0.76 | HPGD (0.48) | HTTHPGDCYP2C19KMT2AALDH1A1 | |
| SCHEMBL16958839 | 0.76 | CES2 (0.47) | LMNACES2CES1KMT2AALDH1A1 | |
| SCHEMBL29875319 | 0.74 | ALDH1A1 (0.41) | TSHRHTTL3MBTL1MAPK1LMNA | |
| SCHEMBL436125 | 0.74 | TSHR (0.41) | TSHRHTTL3MBTL1MAPK1LMNA | |
| SCHEMBL7068869 | 0.74 | TSHR (0.41) | TSHRHTTL3MBTL1MAPK1LMNA | |
| SCHEMBL58239 | 0.74 | MAOA (0.47) | TSHRHTTMAPK1AKT1HPGD | |
| SCHEMBL54072 | 0.74 | KMT2A (0.56) | TSHRHTTL3MBTL1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695295-A1 | 3-(HETERO)ARYL CARBOXYLIC ACID DERIVATIVES, METHODS OF PREPARING THEM AND INTERMEDIATES USED IN THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-07 | — | — | EP | disclosed |
| EP-0183989-A2 | Fluorine-containing graft copolymer and adhesive and composite membrane made thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-06-11 | — | — | EP | disclosed |