Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM6A | O15550 | 1/20 | 0.43 |
| ▸ | TET3 | O43151 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KDM4B | O94953 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.43 |
| ▸ | IL1B | P01584 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308593 | 0.93 | KDM4E (0.46) | KDM4EMAPTL3MBTL1KDM6BKDM6A | |
| SCHEMBL69562 | 0.80 | KDM4E (0.52) | KDM4EMAPTL3MBTL1KDM6BKDM6A | |
| SCHEMBL29415433 | 0.80 | KDM4E (0.52) | KDM4EMAPTL3MBTL1KDM6BKDM6A | |
| SCHEMBL2127197 | 0.78 | KDM4E (0.59) | KDM4EMAPTL3MBTL1KDM6BKDM6A | |
| SCHEMBL2433830 | 0.78 | CYP1A2 (0.39) | KDM4ETDP1ALDH1A1ALOX15TSHR | |
| SCHEMBL2174498 | 0.77 | NR4A1 (0.48) | KDM4EL3MBTL1KDM6BKDM6ATET3 | |
| SCHEMBL2435713 | 0.76 | CYP1A2 (0.41) | KDM4ETDP1ALDH1A1ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL9401935 | 0.75 | NR4A1 (0.47) | KDM4EL3MBTL1KDM6BKDM6ATET3 | |
| SCHEMBL1759011 | 0.73 | KDM4E (0.56) | KDM4EMAPTL3MBTL1KDM6BKDM6A | |
| SCHEMBL23660919 | 0.72 | IL1B (0.53) | KDM4EMAPTL3MBTL1KDM6BKDM6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585382-A | ANTICARCINOGENIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0705250-A1 | BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5416089-A | Antitumor agent | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| WO-1995000490-A1 | BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-01-05 | — | — | WO | disclosed |