SCHEMBL69562

SCHEMBL69562

O=C(O)c1ccc2ncccc2c1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.52
MAPT P10636 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.51
KDM6B O15054 1/20 0.51
KDM6A O15550 1/20 0.51
TET3 O43151 1/20 0.51
KDM4A O75164 1/20 0.51
KDM4B O94953 1/20 0.51
KDM5C P41229 1/20 0.51
KDM4D Q6B0I6 1/20 0.51
TET2 Q6N021 1/20 0.51
ALKBH5 Q6P6C2 1/20 0.51
TET1 Q8NFU7 1/20 0.51
FTO Q9C0B1 1/20 0.51
EGLN1 Q9GZT9 1/20 0.51
KDM4C Q9H3R0 1/20 0.51
KDM2A Q9Y2K7 1/20 0.51
KDM3A Q9Y4C1 1/20 0.51
TDP1 Q9NUW8 1/20 0.48
IL1B P01584 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415433 1.00 KDM4E (0.52) KDM4EMAPTL3MBTL1KDM6BKDM6A
SCHEMBL9308593 0.87 KDM4E (0.46) KDM4EMAPTL3MBTL1KDM6BKDM6A
SCHEMBL2127197 0.84 KDM4E (0.59) KDM4EMAPTL3MBTL1KDM6BKDM6A
SCHEMBL1759011 0.82 KDM4E (0.56) KDM4EMAPTL3MBTL1KDM6BKDM6A
SCHEMBL729995 0.82 ERN1 (0.56) KDM4EMAPTL3MBTL1KDM6BKDM6A
SCHEMBL23660919 0.81 IL1B (0.53) KDM4EMAPTL3MBTL1KDM6BKDM6A
SCHEMBL3986493 0.81 MEN1 (0.58) KDM4EMAPTL3MBTL1KDM6BKDM6A
SCHEMBL10464642 0.81 KDM4E (0.49) KDM4EMAPTL3MBTL1KDM6BKDM6A
SCHEMBL20424060 0.81 LMNA (0.53) KDM4EMAPTL3MBTL1KDM6BKDM6A
SCHEMBL14888067 0.81 KDM4E (0.50) KDM4EMAPTL3MBTL1KDM6BKDM6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108546223-B Process for the manufacture of nitriles and their corresponding amines 中国石化扬子石油化工有限公司 2022-02-11 CN claimed
CN-105016940-A Process for the manufacture of nitriles and their corresponding amines SINOPEC YANGZI PETROCHEMICAL 2015-11-04 CN claimed
CN-105016939-A Preparation methods of nitrile and corresponding amine SINOPEC YANGZI PETROCHEMICAL 2015-11-04 CN claimed
CN-105001032-A Process for the manufacture of nitriles and their corresponding amines SINOPEC YANGZI PETROCHEMICAL 2015-10-28 CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
CN-108546223-B Process for the manufacture of nitriles and their corresponding amines 中国石化扬子石油化工有限公司 2022-02-11 CN disclosed
CN-108164381-B Process for the manufacture of nitriles and their corresponding amines 中国石化扬子石油化工有限公司 2022-02-11 CN disclosed
CN-108546223-A The manufacturing method of nitrile and its corresponding amine 中国石化扬子石油化工有限公司 2018-09-18 CN disclosed
CN-105755480-B Efficient acidic cleaner 江苏筑磊电子科技有限公司 2018-06-19 CN disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed
US-5283335-A Controlling (mono or di)cotyledenous plants AMERICAN CYANAMID COMPANY (US) 1994-02-01 US disclosed
US-4968803-A FLUORINE AS OXIDANT ALLIED-SIGNAL INC. (US) 1990-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 KDM4E 717/4885MAPT 1923/4885L3MBTL1 4274/4885
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 KDM4E 2504/4885MAPT 2575/4885L3MBTL1 4778/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB KDM4E 1615/4885MAPT 2140/4885L3MBTL1 3961/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA KDM4E 1109/4885MAPT 3115/4885L3MBTL1 4438/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA KDM4E 2585/4885MAPT 3104/4885L3MBTL1 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.