Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487846 | 0.89 | AKR1B1 (0.57) | ALDH1A1KDM4ERAB9AAKR1B1AKR1B10 | |
| SCHEMBL9046869 | 0.88 | AKR1B1 (0.53) | ALDH1A1KDM4ERAB9AAKR1B1AKR1B10 | |
| SCHEMBL9049383 | 0.86 | AKR1B1 (0.60) | ALDH1A1KDM4EAKR1B1AKR1B10HDAC1 | |
| SCHEMBL9048794 | 0.81 | LMNA (0.62) | ALDH1A1KDM4ERAB9ATDP1L3MBTL1 | |
| SCHEMBL10487913 | 0.81 | AKR1B1 (0.64) | ALDH1A1KDM4ERAB9AAKR1B1AKR1A1 | |
| SCHEMBL9046143 | 0.80 | AKR1A1 (0.59) | ALDH1A1KDM4EAKR1B1HDAC1HDAC6 | |
| SCHEMBL10487906 | 0.79 | AKR1A1 (0.65) | ALDH1A1KDM4ERAB9AAKR1B1AKR1A1 | |
| SCHEMBL9534320 | 0.79 | MEN1 (0.60) | ALDH1A1AKR1B1AKR1A1KMT2AMEN1 | |
| SCHEMBL10487925 | 0.78 | AKR1B1 (0.61) | ALDH1A1KDM4EAKR1B1AKR1B10AKR1A1 | |
| SCHEMBL10487889 | 0.78 | AKR1B1 (0.52) | ALDH1A1AKR1B1AKR1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456835-B1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN SEIYAKU KK (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5234928-A | Inhibit platelet aggregation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0456835-A1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |