Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567990 | 0.83 | TRPM8 (0.47) | TRPM8HSD11B1ALDH1A1LMNA | |
| SCHEMBL9046594 | 0.82 | PTGIR (0.36) | TRPM8NPSR1SCN1ASCN5ASCN9A | |
| SCHEMBL9048474 | 0.82 | PTGIR (0.36) | SCN1ASCN5ASCN9A | |
| SCHEMBL9048479 | 0.82 | PTGIR (0.50) | SCN1ASCN5ASCN9A | |
| SCHEMBL9427074 | 0.76 | TRPM8 (0.35) | TRPM8HSD11B1ALDH1A1PKM | |
| SCHEMBL9048929 | 0.75 | TDP1 (0.36) | TRPM8ALDH1A1LMNATDP1 | |
| SCHEMBL9050469 | 0.74 | KMT2A (0.36) | TRPM8ALDH1A1TDP1 | |
| SCHEMBL9047990 | 0.74 | EPHX1 (0.36) | TRPM8 | |
| SCHEMBL11636914 | 0.72 | SIRT1 (0.44) | TRPM8AKR1C3GAAMAPTALDH1A1 | |
| SCHEMBL9050555 | 0.71 | NPSR1 (0.47) | NPSR1ALDH1A1HPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |