Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048479 | 0.87 | PTGIR (0.50) | PTGIRSCN1ASCN5ASCN9ADRD2 | |
| SCHEMBL9046599 | 0.85 | PTGIR (0.41) | PTGIRSCN1ASCN5ASCN9ATAS1R3 | |
| SCHEMBL9048469 | 0.82 | TRPM8 (0.34) | SCN1ASCN5ASCN9A | |
| SCHEMBL9427127 | 0.79 | PTGIR (0.43) | PTGIRDRD4 | |
| SCHEMBL9567990 | 0.78 | TRPM8 (0.47) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9048934 | 0.77 | PTGIR (0.39) | PTGIRDRD4 | |
| SCHEMBL9427080 | 0.77 | PTGIR (0.39) | PTGIRDRD4 | |
| SCHEMBL9047991 | 0.76 | PTGIR (0.38) | PTGIRDRD4 | |
| SCHEMBL9050562 | 0.76 | NPSR1 (0.43) | PTGIRSCN1ASCN5ASCN9ATAS1R3 | |
| SCHEMBL9050478 | 0.76 | PTGIR (0.39) | PTGIRDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |