Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.78 |
| ▸ | DRD2 | P14416 | 4/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.78 |
| ▸ | HTR1A | P08908 | 3/20 | 0.78 |
| ▸ | HTR2A | P28223 | 3/20 | 0.78 |
| ▸ | DRD3 | P35462 | 3/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.78 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.78 |
| ▸ | MLNR | O43193 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | PGR | P06401 | 2/20 | 0.78 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.78 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.78 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904892 | 0.91 | OPRM1 (0.70) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| Pimozide SCHEMBL29381325 | 0.88 | DRD2 (1.00) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| Pimozide SCHEMBL41584 | 0.88 | DRD2 (1.00) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| Pimozide SCHEMBL14127068 | 0.88 | DRD2 (1.00) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| Pimozide SCHEMBL29031811 | 0.87 | DRD2 (0.98) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| SCHEMBL12863786 | 0.87 | DRD2 (0.98) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| Pimozide SCHEMBL572869 | 0.87 | DRD2 (0.98) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| Pimozide SCHEMBL14894944 | 0.84 | DRD2 (0.89) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| SCHEMBL904891 | 0.83 | OPRM1 (0.72) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| SCHEMBL10034840 | 0.83 | OPRM1 (0.91) | OPRM1CHRM1DRD2KCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |